WebDownload scientific diagram Box plots of fetal hemoglobin (HbF) level measured as percentage of total hemoglobin ( a ) and grams per deciliter ( b ) according to Xmn I genotype among patients ... WebSep 1, 1985 · 5-AZACYTIDINE (5-aza), a cell-cycle-specific DNA hypomethylating agent, 1 has been shown to increase fetal hemoglobin (HbF) production in animals, 2, 3 in one individual with thalassemia, 4 and in several individuals with sickle cell (SS) anemia. 5, 6 In the first phase of our study 5 of repeated doses of 5-aza in one SS patient treated for 100 …
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