WebAug 2, 2024 · Hypersensitivity reactions (HSRs) to chemotherapy agents can present a serious challenge to treating patients with preferred or first-line therapies. Allergic reactions through an immunologic mechanism have been established for platinum and taxane agents, which are used to treat a wide variety of cancers including gynecologic cancers. Platin … WebPaclitaxel was initially administered at 135 mg/m2 over 3 hours every 3 weeks without filgrastim support; the dose was increased as tolerated to a maximum of 175 mg/m2. …
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http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Paclitaxel_monograph.pdf WebApr 14, 2024 · To determine if a gradual, three-step infusion rate titration decreases the rate and severity of immediate HSRs during first and second lifetime exposures to paclitaxel and docetaxel. METHODS We used a prospective, interventional design with historical comparisons to evaluate a sample of 222 first and second lifetime exposure paclitaxel … swarthmore time zone
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WebAug 7, 1990 · Taxol is an antitumor agent in clinical trial that has been shown to have activity against advanced ovarian carcinoma and melanoma. Hypersensitivity reactions (HSRs) have been one of the toxicities observed with administration of this drug. Of 301 patients treated, 32 patients have had definite (27 … Hypersensitivity reactions from taxol Webtation for paclitaxel administration. Results from this project were the basis for reinstating a standard order set, which includes titration during the rst and second paclitaxel infusions to maximize patient safety. AT A GLANCE Best practices in administration of paclitaxel infusions may vary among oncology settings. Retrospective chart reviews WebOur Story Materials Research Laboratory at UCSB: an NSF MRSEC swarthmore theater md